Design, biological activity and signaling pathway of bovine consensus omega interferon expressed in Pichia pastoris

M Gao, Y Guo, X Luo, J Du, Y Wang, C Cao… - Molecular …, 2019 - Elsevier
… Therefore, a consensus BoIFN-ω (CoBoIFN-ω) was designed and characterized in this
study, and was demonstrated to have antiviral and antiproliferative activities, transduce signals …

[HTML][HTML] Cloning, prokaryotic soluble expression, and analysis of antiviral activity of two novel feline IFN-ω proteins

X Wang, F Li, M Han, S Jia, L Wang, X Qiao, Y Jiang… - Viruses, 2020 - mdpi.com
activity in Vero, F81 (feline kidney cell), Madin–Darby bovine … -species antiviral activity than
the INTERCAT IFN antiviral drug… Homology and phylogenetic tree analysis of the feline IFN-ω …

[HTML][HTML] A novel type-I interferon family, bovine interferon-chi, is involved in positive-feedback regulation of interferon production

Y Guo, Z Song, C Li, Y Yu, H Dai, X Luo… - Frontiers in …, 2020 - frontiersin.org
… on the bovine genome (5). Here, we characterize and measure the activity and regulation of
… have the typical molecular characteristics of type-I IFNs; exhibit antiviral and antiproliferative …

[HTML][HTML] Cross-species genome-wide analysis reveals molecular and functional diversity of the unconventional interferon-ω subtype

LE Shields, J Jennings, Q Liu, J Lee, W Ma… - Frontiers in …, 2019 - frontiersin.org
… their antiviral and inflammatory regulation, we characterized … -ω subtype has evolved several
novel features, which include: … that have much higher antiviral potency than typical IFN-α (14…

Interferon-beta, interferon-gamma and their fusion interferon of Siberian tigers (Panthera tigris altaica) in China are involved in positive-feedback regulation of …

M Mu, H Zhao, Y Wang, M Guo, X Nie, Y Liu… - Developmental & …, 2021 - Elsevier
… A total of 13 interferon sequences from various animals were included in this analysis. The
… biological function, we detected their antivirus activities using cytopathic inhibition test and …

Potential role of the antimicrobial peptide Tachyplesin III against multidrug-resistant P. aeruginosa and A. baumannii coinfection in an animal model

J Qi, R Gao, C Liu, B Shan, F Gao, J He… - Infection and Drug …, 2019 - Taylor & Francis
… Lung histological analysis The lung tissue histology analysis was performed as previously
described. Citation35 Briefly, the left lung tissues were harvested from mice the day after …

重组牛IFN-ω12 生物学特性及其免疫调节机制的研究.

安东, 田其真, 曹斌, 刘静, 周宁… - Chinese Journal of …, 2023 - search.ebscohost.com
… -棕12 has antiviral and anti-proliferating activities with low … , and activate the luciferase
activity activated by the promoter … Molecular cloning and characterization of a novel bovine IFN-…